"May not the sentient Principle have its Seat in some Place in the Brain, where the Nerves terminate, like the Musician shut up in his Organ-Room? May not the infinite Windings, Convolutions, and Complications of the Beginning of the Nerves which constitute the Brain, serve to determin their particular Tone, Tension, and consequently the Intestin Vibrations of their Parts? "
— Cheyne, George (1671-1743)
See The English Malady: or, a Treatise of Nervous Diseases of All Kinds, As Spleen, Vapours, Lowness of Spirits, Hypochondriacal, and Hysterical Distempers, &c. In Three Parts. Part I. of the Nature and Cause of Nervous Distempers. Part II. of the Cure of Nervous Distempers. Part III. Variety of Cases That Illustrate and Confirm the Method of Cure. With the Author’s Own Case at Large. (London: Printed for G. Strahan in Cornhill, and J. Leake at Bath, 1733). <Link to ESTC>